Thermo Fisher Scientific CYP19A1 Monoclonal Antibody (2B6)

Applications

Tested Dilution

Publications

ELISA (ELISA)

0.3 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

2B6

Immunogen

CYP19A1 (AAH35714, 48 a.a. approximately 218 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Aromatase,uniProtId:P11511-1,ncbiNodeId:9606,antigenRange:1-503,antigenLength:503,antigenImageFileName:H00001588-M03_Aromatase_P11511-1_House_mouse.svg,antigenImageFileNamePDP:H00001588-M03_Aromatase_P11511-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: PGPGYCMGIG PLISHGRFLW MGIGSACNYY NRVYGEFMRV WISGEETLII SKSSSMFHIM KHNHYSSRFG SKLGLQCIGM HEKGIIFNNN PELWKTTRPF FMKALSGPGL VRMVTVCAES LKTHLDRLEE VTNESGYVDV LTLLRRVMLD TSNTLFLRIP LDGTEIFTLT S

Target Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.