Thermo Fisher Scientific CYP19A1 Monoclonal Antibody (2B6)
인간 CYP19A1 단백질을 인식하는 Mouse monoclonal antibody(클론 2B6). ELISA에 적합하며, 비결합형 액상 형태. PBS(pH 7.4) 버퍼 내 보존제로 없이 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- ELISA (ELISA)
Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B6 |
| Immunogen | CYP19A1 (AAH35714, 48 a.a. approximately 218 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
PGPGYCMGIG PLISHGRFLW MGIGSACNYY NRVYGEFMRV WISGEETLII SKSSSMFHIM KHNHYSSRFG SKLGLQCIGM HEKGIIFNNN PELWKTTRPF FMKALSGPGL VRMVTVCAES LKTHLDRLEE VTNESGYVDV LTLLRRVMLD TSNTLFLRIP LDGTEIFTLT S
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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