Thermo Fisher Scientific DAB2 Monoclonal Antibody (1C8)
DAB2 단백질을 인식하는 Mouse IgG2a 형 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 시료 반응성이 있으며, PBS 기반 액상 형태로 제공됩니다. 연구용으로 사용되며, -20°C에서 보관이 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C8 |
| Immunogen | DAB2 (NP_001334, 673–770 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
QTSSGTLSAF ASYFNSKVGI PQENADHDDF DANQLLNKIN EPPKPAPRQV SLPVTKSTDN AFENPFFKDS FGSSQASVAS SQPVSSEMYR DPFGNPFA
Target Information
DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The predicted 770-amino acid protein shows 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein. Homology is strongest in the amino-terminal region corresponding to the phosphotyrosine interaction domain. Down-regulation of DAB2 may play an important role in ovarian carcinogenesis.
This gene was initially named DOC2 (Differentially expressed in Ovarian Cancer) and is distinct from DOC2A and DOC2B genes (double C2-like domains, alpha and beta).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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