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Thermo Fisher Scientific Phospho-CK1 alpha (Tyr294) Polyclonal Antibody
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Phospho-CK1 alpha (Tyr294) 폴리클로날 항체로 인산화된 CK1α의 Tyr294 잔기를 특이적으로 인식합니다. Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능하며, 사람·생쥐·랫트 반응성을 가집니다. 고순도 정제, -20°C 보관.
- 카탈로그번호
- PA5103266
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오전 10:35
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Thermo Fisher Scientific PA5103266 Phospho-CK1 alpha (Tyr294) Polyclonal Antibody 100 ul pk판매 단위 pk ·
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614,900원VAT 포함 676,390원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-CK1 alpha (Tyr294) Polyclonal Antibody
Thermo Fisher Scientific Phospho-CK1 alpha (Tyr294) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CSNK1A1 (Accession P48729), corresponding to amino acid residues around phosphorylated Tyr294 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815965 |
Product Specific Information
Antibody detects endogenous levels of Casein Kinase 1 alpha only when phosphorylated at Tyr294.
Target Information
CNSK1A1 (CK1 alpha 1) is a member of the casein kinase I (CKI) gene family, encoding serine/threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric (25–55 kDa) and found in nuclei, cytoplasm, and membrane fractions of eukaryotic cells.
Functions include:
- Phosphorylation of multiple proteins
- Participation in Wnt signaling
- Phosphorylation of CTNNB1 at Ser-45
- Possible phosphorylation of PER1 and PER2
- Potential role in chromosome segregation during mitosis
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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