Thermo Fisher Scientific KCNIP2 Monoclonal Antibody (OTI14A7), TrueMAB
인간 KCNIP2 단백질을 인식하는 Mouse IgG2b 단클론 항체로 Western blot에 적합. TrueMAB 형식으로 높은 특이성과 재현성을 제공. 액상 형태로 PBS/BSA/glycerol 버퍼에 보관하며 -20°C에서 안정적 저장 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI14A7 |
| Immunogen | Full length human recombinant protein of human KCNIP2 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Voltage-gated potassium (Kv) channels are key components of the potassium currents in the heart and central nervous system.
In the heart, Kv4 channels are involved in the repolarization phase of the action potential.
In the brain, these channels prevent reverse-propagation of action potentials.
Found associated with Kv4 channels are a group of calcium-binding proteins termed KChIPs (Kv channel interacting proteins).
KChIPs are small molecular weight proteins that bind to the cytoplasmic amino termini of Kv4 alpha-subunits and modulate its function.
There are currently three known KChIPs:
- KChIP1: Expressed in the brain
- KChIP2: Expressed in the brain, heart, and lung; has three isoforms (a, b, c)
- KChIP3: Also known as calsenilin and DREAM (DRE-antagonist modulator); expressed in the brain and testis
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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