Thermo Fisher Scientific KCNIP2 Monoclonal Antibody (OTI10H1), TrueMAB
인간 KCNIP2 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화됨. TrueMAB 포맷으로 제공되며, 고순도 친화 크로마토그래피 정제. 액상 형태로 안정적이며 연구용으로만 사용 가능.
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Thermo Fisher Scientific KCNIP2 Monoclonal Antibody (OTI10H1), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10H1 |
| Immunogen | Full length human recombinant protein of human KCNIP2 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Voltage-gated potassium (Kv) channels are key components of potassium currents in the heart and central nervous system. In the heart, Kv4 channels participate in the repolarization phase of the action potential, while in the brain they prevent reverse-propagation of action potentials.
Kv4 channels are associated with calcium-binding proteins called KChIPs (Kv channel interacting proteins). KChIPs bind to the cytoplasmic amino termini of Kv4 alpha-subunits and modulate their function.
Known KChIPs include:
- KChIP1: Expressed in the brain
- KChIP2: Expressed in the brain, heart, and lung; has isoforms a, b, and c
- KChIP3: Also known as calsenilin or DREAM; expressed in the brain and testis
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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