Thermo Fisher Scientific MATN3 Polyclonal Antibody
MATN3 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Mouse 및 Rat 시료에 반응하며 Western blot과 ELISA에 적합합니다. 고순도 Affinity Chromatography 정제, 안정적인 액상 형태로 제공됩니다. 연구용 전용 제품입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 277–486 of human MATN3 (NP_002372.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.68 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914697 |
Product Specific Information
- Positive test controls: Mouse liver, Mouse brain, Rat liver
- Localization: Secreted
Immunogen sequence:
HVCISDGEGK HHCECSQGYT LNADKKTCSA LDRCALNTHG CEHICVNDRS GSYHCECYEG YTLNEDRKTC SAQDKCALGT HGCQHICVND RTGSHHCECY EGYTLNADKK TCSVRDKCAL GSHGCQHICV SDGAASYHCD CYPGYTLNED KKTCSATEEA RRLVSTEDAC GCEATLAFQD KVSSYLQRLN TKLDDILEKL KINEYGQIHR
Target Information
Matrilins (MATNs) are a family of non-collagenous extracellular matrix (ECM) proteins consisting of four known members that play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs).
MATN1 and MATN3 are specifically expressed in cartilage and are among the most up-regulated ECM proteins during chondrogenesis.
MATN3 includes a single N-terminal von Willebrand Factor A (vWFA) domain, four epidermal growth factor (EGF) repeats, and a coiled-coil domain.
Mutations in MATN3 are associated with inherited chondrodysplasias, and aberrant expression is linked to cartilaginous neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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