Thermo Fisher Scientific ORC4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 187-436 of human ORC4L (NP_002543.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ORC4,uniProtId:O43929-1,ncbiNodeId:9606,antigenRange:187-436,antigenLength:436,antigenImageFileName:PA5-121127_ORC4_O43929-1_Rabbit.svg,antigenImageFileNamePDP:PA5-121127_ORC4_O43929-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.23 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914699

Product Specific Information

Positive test controls include: HeLa, MCF7, Mouse brain. The target is usually found in the following locations: Nucleus.

Immunogen sequence: IAVIGLTCRL DILELLEKRV KSRFSHRQIH LMNSFGFPQY VKIFKEQLSL PAEFPDKVFA EKWNENVQYL SEDRSVQEVL QKHFNISKNL RSLHMLLMLA LNRVTASHPF MTAVDLMEAS QLCSMDSKAN IVHGLSVLEI CLIIAMKHLN DIYEEEPFNF QMVYNEFQKF VQRKAHSVYN FEKPVVMKAF EHLQQLELIK PMERTSGNSQ REYQLMKLLL DNTQIMNALQ KYPNCPTDVR QWATSSLSWL

Target Information

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.