Thermo Fisher Scientific ORC4 Polyclonal Antibody
Human 및 Mouse 시료에 반응하는 Rabbit Polyclonal ORC4 항체로, Western blot과 ELISA에 사용 가능. 핵 내 ORC4 단백질 검출에 적합하며, 고순도의 Affinity Chromatography 정제 제품. -20°C 보관, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 187–436 of human ORC4L (NP_002543.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.23 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914699 |
Product Specific Information
- Positive test controls: HeLa, MCF7, Mouse brain
- Subcellular localization: Nucleus
Immunogen sequence:
IAVIGLTCRL DILELLEKRV KSRFSHRQIH LMNSFGFPQY VKIFKEQLSL PAEFPDKVFA EKWNENVQYL SEDRSVQEVL QKHFNISKNL RSLHMLLMLA LNRVTASHPF MTAVDLMEAS QLCSMDSKAN IVHGLSVLEI CLIIAMKHLN DIYEEEPFNF QMVYNEFQKF VQRKAHSVYN FEKPVVMKAF EHLQQLELIK PMERTSGNSQ REYQLMKLLL DNTQIMNALQ KYPNCPTDVR QWATSSLSWL
Target Information
The origin recognition complex (ORC) is a highly conserved six-subunit protein complex essential for the initiation of DNA replication in eukaryotic cells.
Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins.
This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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