Thermo Fisher Scientific SFRS8 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human SFRS8 protein. Validated for Western blot and immunocytochemistry. Supplied as a liquid, unconjugated form in PBS with glycerol. Suitable for research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SFSWAP (Accession Q12872), corresponding to amino acid residues K134–N184. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851345 |
Product Specific Information
Antibody detects endogenous levels of total SFRS8.
Target Information
Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Although the function of SIPA1L2 is not fully understood, deregulation of related SIPA proteins can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on homology, SIPA1L2 likely contributes to embryo development and cell proliferation, potentially including oncogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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