Thermo Fisher Scientific Human DAPK1, GST Tag Recombinant Protein

Thermo Fisher Scientific Human DAPK1, GST Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution

• Assay-dependent

Product Specifications

Product Specific Information

• For maximum recovery, please spin prior to use.
• Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use materials in original packaging until exhausted.
• For larger sizes, reduce freeze/thaw cycles by preparing aliquots (not below 20 µL).
• Do not store kinase diluted.
• Properly stored at -80°C, guaranteed for 6 months from date of purchase.
• Protein Form: Catalytic

Target Information

DAPK1 (Death-associated protein kinase 1) is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and acts as a potential tumor suppressor.
It participates in multiple cellular signaling pathways regulating cell survival, apoptosis, and autophagy.
DAPK1 mediates both caspase-dependent type I apoptotic and caspase-independent type II autophagic cell death.
It phosphorylates PIN1, inhibiting its catalytic activity and nuclear localization, and also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.