Thermo Fisher Scientific Human EPHB1, GST Tag Recombinant Protein

Thermo Fisher Scientific Human EPHB1, GST Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution

• Assay-dependent

Product Specifications

Product Specific Information

• For maximum recovery, please spin prior to use.
• Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use original packaging until exhausted.
• For larger sizes, aliquot preparation may reduce freeze/thaw cycles; aliquots below 20 µL are not recommended.
• Do not store diluted kinase.
• Properly stored at -80°C, product is guaranteed for 6 months from date of purchase.

Protein Form: Cytoplasmic

Target Information

EPHB1 is a receptor tyrosine kinase belonging to the ephrin receptor family. Eph family kinases play key roles in processes such as nervous system development, angiogenesis, and synapse formation and maturation. EphB1 and related proteins are type I membrane-spanning receptors with immunoglobulin, fibronectin type III, and cysteine-rich domains in the ectodomain, and a cytoplasmic tyrosine kinase domain upstream of a SAM domain.

EphB family proteins bind B-class ephrins, which are transmembrane ligands capable of bidirectional signaling. EphB1 is predominantly expressed in developing neural structures and vascular epithelium of kidney and other tissues. Upon binding ephrin B1, EphB1 regulates cell attachment and cell–cell assembly, playing roles in neuronal and vascular cell targeting.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.