Thermo Fisher Scientific STAT6 Polyclonal Antibody
STAT6 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC 및 IHC(Paraffin)에서 1:100~1:500 희석으로 사용 가능. 인간 반응성, 다양한 종에 예측 반응. IL-4 및 IL-13 매개 면역 반응 연구에 적합. 연구용 한정.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 600 and 650 of Human Signal Transducer and Activator of Transcription 6 (STAT6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, Dog, Horse, Rabbit, Guinea pig, Pig, Golden hamster, Panda, Orangutan, Monkey, Gorilla, and Chimpanzee
Target Information
STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 (IL-4) and interleukin-13 (IL-13).
STAT6-deficient (Stat6-/-) models show impaired IL-4-mediated functions such as Th2 helper T-cell differentiation, expression of surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4-mediated proliferation.
STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung, and placenta.
STAT6 is critically involved in Th2 immune response and exists in two isoforms: STAT6a and STAT6c.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: IHC-00209_STAT6_P42226-1_Rabbit.svg, IHC-00209_STAT6_P42226-1_Rabbit_PDP.jpeg)
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