Thermo Fisher Scientific BANF1 Polyclonal Antibody
BANF1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며, 인간 및 생쥐 시료 반응. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (IHC) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide from near the carboxy terminus of human BANF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153647 |
Product Specific Information
Despite its predicted molecular weight, BANF1 often migrates at a higher molecular weight in SDS-PAGE.
A suggested positive control is human kidney tissue lysate.
PA5-20328 can be used with blocking peptide PEP-0448.
Target Information
Barrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double-stranded DNA. BANF1 interacts with nuclear proteins such as LAP2, emerin, and MAN1, and is a host cell component of retroviral pre-integration complexes (PICs), including that of HIV.
BANF1 binds to p55 Gag and its cleaved product matrix, and may contribute to HIV-1 PIC assembly or activity through direct binding to matrix and DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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