Thermo Fisher Scientific FXIIIA Polyclonal Antibody, Biotin
FXIIIA 단백질을 표적으로 하는 Thermo Fisher Scientific의 Biotin 결합 Rabbit Polyclonal Antibody. Western blot, ELISA, IP에 적합하며 다양한 종(Cat, Human, Mouse, Non-human primate)에 반응. 고순도 Affinity chromatography 정제 및 안정적 액상 포맷 제공.
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- FXIIIA101BIOTIN
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Thermo Fisher Scientific FXIIIA Polyclonal Antibody, Biotin
Applications and Tested Dilutions
- Western Blot (WB): 1:500–1:1,000
- ELISA: 1:10,000
- Immunoprecipitation (IP): 1:50–1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cat, Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 1–50 on human factor XIII A subunit protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) containing 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The FXIIIA gene encodes the coagulation factor XIII A subunit, which is the final zymogen activated in the blood coagulation cascade. Plasma factor XIII consists of two A subunits (catalytic) and two B subunits (carrier). Upon activation by thrombin and calcium, the A subunits form the active enzyme factor XIIIa, functioning as a transglutaminase that stabilizes fibrin clots by crosslinking fibrin molecules and other proteins such as alpha-2-plasmin inhibitor and fibronectin.
Deficiency in factor XIII can lead to bleeding disorders, impaired wound healing, and habitual abortion. It is categorized into type I (lack of both A and B subunits) and type II (lack of A subunit only).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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