Thermo Fisher Scientific TRPM2 Polyclonal Antibody
TRPM2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot과 IHC에 사용 가능. 합성 펩타이드 항원을 기반으로 제작되었으며, 인간 시료에 반응. 동결건조 형태로 제공되며 장기 보관 시 -20°C에서 안정적.
- 카탈로그번호
- OST00346W-100UL
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host/Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the C-terminal region of human TRPM2 (TRPC7, LTRPC2) conjugated to an immunogenic carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: TRPM2
Target Information
TRPM2 belongs to the ion transport protein family, which includes sodium, potassium, and calcium ion channels. This family is characterized by proteins possessing six transmembrane helices, with the last two flanking a loop that determines ion selectivity.
TRPM2 is activated by oxidative stress and confers susceptibility to cell death. It is a calcium-permeable cation channel regulated by free intracellular ADP-ribose.
Several alternatively spliced transcript variants of the TRPM2 gene have been described, but their full-length nature is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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