Thermo Fisher Scientific IRE1 Polyclonal Antibody
Thermo Fisher Scientific의 IRE1 Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가지며 Western blot, ELISA, Immunoprecipitation에 적합합니다. 합성 펩타이드 면역원으로 제작된 비결합 폴리클로날 항체로, 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to unique amino acid sequence within amino acid region 900–1000 on human IRE1A protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ERN1 serine/threonine kinase, also known as endoplasmic reticulum to nucleus signaling 1 (IRE1), is a human homologue of the yeast Ire1 gene product. It possesses intrinsic kinase and endoribonuclease activity and plays a key role in ER-based stress signaling. ERN1 controls IRE1 proteolysis in mammalian cells and is essential for fetal viability in extraembryonic cells. IRE1 acts as a sensor of unfolded proteins in the ER, initiating the unfolded protein response by splicing XBP1 mRNA, converting it into a potent transcriptional activator. Null mutants are viable but essential under stress conditions that cause unfolded proteins to accumulate in the ER. Depletion of IRE1p through dominant negative expression leads to apoptosis under such stress conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific IRE1 Polyclonal Antibody, Biotin
594,400원
Thermo Fisher Scientific
Thermo Fisher Scientific IRE1A Polyclonal Antibody
449,700원
Thermo Fisher Scientific
Thermo Fisher Scientific IRE1 Polyclonal Antibody
449,700원
Thermo Fisher Scientific
Thermo Fisher Scientific IRAKM Polyclonal Antibody
449,700원
Thermo Fisher Scientific
Thermo Fisher Scientific IRAKM Polyclonal Antibody, Biotin
594,400원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|