Thermo Fisher Scientific CCR3 Polyclonal Antibody
CCR3 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 및 비인간 영장류 반응성. IHC(P)에서 8 µg/mL로 검증됨. 항원 친화 크로마토그래피로 정제, PBS buffer 및 0.1% sodium azide 포함. 연구용으로만 사용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 8 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from C-terminus of human CCR3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550777 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Monkey: 100%
- Gibbon: 94%
- Marmoset, Dog, Rabbit: 88%
- Mouse, Bovine, Hamster, Horse: 81%
Target Information
CCR3 (C-C chemokine receptor type 3) binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1 delta.
CCR3 transduces signals by increasing intracellular calcium ion levels and also serves as an alternative co-receptor with CD4 for HIV-1 infection.
Chemokines play crucial roles in inflammation and recruitment of effector immune cells. They activate leukocytes via G protein-coupled receptors.
Chemokine receptors are classified into two major groups: CXCR and CCR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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