Thermo Fisher Scientific KLF10 Monoclonal Antibody (3F7)
KLF10 단백질을 표적으로 하는 Mouse IgG2a monoclonal antibody. Western blot 및 ELISA에 적합하며, 인간 시료 반응성. Affinity chromatography로 정제된 액상 형태로 제공되며, PBS buffer에 보존제 미포함. 연구용으로만 사용 가능.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Thermo Fisher Scientific KLF10 Monoclonal Antibody (3F7)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3F7 |
| Immunogen | KLF10 (AAH11538.1, 1–110 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MEERMEMISE RPKESMYSWN KTAEKSDFEA VEALMSMSCS WKSDFKKYVE NRPVTPVSDL SEEENLLPGT PDFHTIPAFC LTPPYSPSDF EPSQVSNLMA PAPSTVHFKS
Target Information
KLF10 is a nuclear protein belonging to the Sp1 C2H2-type zinc-finger protein family with three C2H2-type zinc fingers. It acts as a transcriptional repressor regulating cell growth and is induced by TGF-beta, linking TGF-beta-mediated signaling to pancreatic epithelial cell regulation. KLF10 promotes apoptosis through the mitochondrial pathway and may inhibit Smad7 expression in bronchial epithelial cells.
It is ubiquitously expressed in tissues and may mediate up-regulation of TGFBI in VHL-deficient tumors. Overexpression is associated with renal clear cell carcinoma and other cancers.
KLF11, a related zinc finger transcription factor, binds SP1-like sequences to inhibit cell growth and induce apoptosis. Defects in KLF11 cause maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific KLF10 Monoclonal Antibody (4D12)
518,100원
Thermo Fisher Scientific
Thermo Fisher Scientific KLF10 Monoclonal Antibody (3H3)
518,100원
Thermo Fisher Scientific
Thermo Fisher Scientific KLF10 Monoclonal Antibody (3F7)
518,100원
Thermo Fisher Scientific
Thermo Fisher Scientific THRA Polyclonal Antibody, MaxPab
518,100원
Thermo Fisher Scientific
Thermo Fisher Scientific THY1 Monoclonal Antibody (3F9)
518,100원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|