Thermo Fisher Scientific ANKRD32 Polyclonal Antibody
Rabbit polyclonal antibody against human ANKRD32. Validated for ICC/IF applications. Antigen affinity purified and supplied as a liquid in PBS with 40% glycerol. Suitable for DNA damage response and genomic stability research.
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Applications
Immunocytochemistry (ICC/IF)
- Tested dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human ANKRD32. Recombinant protein control fragment (Product #RP-106517) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664569 |
Product Specific Information
Immunogen sequence:
SWLQMFVAEAV FKKLCLQSSG SVSSEPLSLQ KMVYSYLPAL GKTGVLGSGK IQVSKKIGQR PCFDSQRTLL MLNGTKQKQV EGLP
- Highest antigen sequence identity to orthologs: mouse 67%, rat 67%
Target Information
ANKRD32 plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and maintaining genomic stability (PubMed:25931565).
The SLF1-SLF2 complex links RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) during DNA repair in response to stalled replication forks.
It promotes the recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions (PubMed:25931565).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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