Thermo Fisher Scientific DCAF6 Polyclonal Antibody
Rabbit polyclonal antibody against human DCAF6, validated for ICC/IF. Recombinant human DCAF6 used as immunogen. High specificity and affinity purified by antigen affinity chromatography. Supplied in PBS with 40% glycerol, suitable for research use only.
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Applications
Immunocytochemistry (ICC/IF)
- Tested dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human DCAF6. Recombinant protein control fragment (Product #RP-106523) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663493 |
Product Specific Information
Immunogen sequence:
EDVTKYQEGVS AENPVENHIN ITQSDKFTAK PLDSNSGERN DLNLDRSCGV PEESASSEKA KEPETSDQTS TESATNENNT NPEPQFQTEA TG
Highest antigen sequence identity to the following orthologs:
- Mouse: 45%
- Rat: 47%
Target Information
NRIP is a novel 860 amino acid nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and upregulates their transcriptional activity, functioning as a nuclear receptor coactivator.
The role of NRIP has been implicated in cell growth and in cervical and prostate cancer, indicating potential therapeutic relevance.
Northern blot analysis shows high expression of NRIP in skeletal muscle and testis, with lower expression in heart, prostate, and adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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