Thermo Fisher Scientific BFSP1 Monoclonal Antibody (OTI3H6), TrueMAB
BFSP1 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 파라핀 포매 조직면역염색에 적합. 고순도 친화 크로마토그래피 정제. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 405–665 of human BFSP1 produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The vertebrate ocular lens is composed primarily of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (phakinin) and filensin (product of the BFSP1 gene), are expressed after fiber cell differentiation begins.
These proteins form a unique cytoskeletal element known as the beaded filament (BF).
Mutations in the BFSP1 gene are associated with autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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