Thermo Fisher Scientific IL1RAPL1 Monoclonal Antibody (3E3D12)
IL1RAPL1 단백질을 인식하는 Mouse monoclonal antibody. Western blot, ICC/IF, Flow Cytometry, ELISA에 사용 가능. Human 시료 반응성. Protein G로 정제된 액상형 항체로, 1 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E3D12 |
| Immunogen | Purified recombinant fragment of human IL1RAPL1 (AA: 541–694) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787401 |
Product Specific Information
MA5-31778 has been tested in indirect ELISA.
Target Information
The IL1RAPL1 gene encodes a protein belonging to the interleukin 1 receptor family, similar to interleukin 1 accessory proteins. It includes an N-terminal signal peptide, three extracellular Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail that interacts with multiple signaling molecules.
This gene is located on the X chromosome region associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations have been identified in patients with intellectual disability. It is highly expressed in postnatal brain structures involved in the hippocampal memory system, suggesting a specialized role in memory and learning processes, and contributes to synapse formation and stabilization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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