Thermo Fisher Scientific KV4.2 (KCND2) Monoclonal Antibody (5B11B9)
KV4.2(KCND2) 단백질을 인식하는 Mouse monoclonal 항체로, WB, Flow Cytometry, ELISA에 적합. 정제된 human KCND2 재조합 단백질(AA 27-184)을 면역원으로 사용. 1 mg/mL 농도의 액상 형태이며, 단백질 G로 정제됨. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5B11B9 |
| Immunogen | Purified recombinant fragment of human KCND2 (AA: 27–184) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4 °C short term. For long-term storage, store at −20 °C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787405 |
Product Specific Information
MA5-31782 has been tested in indirect ELISA.
Target Information
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes—shaker, shaw, shab, and shal—have been identified in Drosophila, and each has human homologs.
This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, which forms voltage-activated A-type potassium ion channels and is prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current that is not under N-terminus control as in Shaker channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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