Thermo Fisher Scientific Chitotriosidase Monoclonal Antibody (1D9G2,1D9G4,2B4G3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1D9G2,1D9G4,2B4G3

Immunogen

Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Chitotriosidase,uniProtId:Q13231-1,ncbiNodeId:9606,antigenRange:22-137,antigenLength:466,antigenImageFileName:MA5-15482_Chitotriosidase_Q13231-1_House_mouse.svg,antigenImageFileNamePDP:MA5-15482_Chitotriosidase_Q13231-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.03% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_10977708

Product Specific Information

MA5-15482 targets CHIT1 in indirect ELISA, WB applications and shows reactivity with Human samples.

The MA5-15482 immunogen is purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli.
.

Target Information

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.