Thermo Fisher Scientific PKP3 Monoclonal Antibody (7F6)
PKP3 단백질을 인식하는 Mouse monoclonal 항체로 Western blot, IHC, IP 등 다양한 응용에 사용 가능. Human 및 Mouse에 반응하며, 단백질 신호전달 및 세포간 결합 연구에 적합. 1 mg/mL 농도의 액상 형태로 제공되며 Protein A로 정제됨.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7F6 |
| Immunogen | Recombinant fragment corresponding to amino acids 1–308 of Human Plakophilin 3 fused to maltose binding protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539463 |
Product Specific Information
This target has a predicted molecular weight of approximately 87 kDa.
Target Information
Plakophilin-3 is an Armadillo-like protein localized in both nuclei and desmosomes of epithelial cells. Its expression is largely restricted to epithelial tissues. It shows punctate staining along cell borders typical of desmosomal proteins and bright nuclear speckles, indicating dual localization in desmosomal plaques and nuclei. This suggests a role in signal transduction between the plasma membrane and the nucleus. The human protein has a predicted molecular mass of ~87 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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