Thermo Fisher Scientific UMPS Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Immunogen sequence:
  TKDYGTKRLV EGTINPGETC LIIEDVVTSG SSVLETVEVL QKEGLKVTDA IVLLDREQGG KDKLQAHGIR LHSVCTLSKM LEILEQQKKV DAETVGRVKR FIQENVFVAA NHNGSPLSIK EAPKELSFGA RAELPRIHPV ASKLLRLMQK KETNLCLSAD V
• Positive Samples: HT-29, U-87MG, HeLa, LO2, Mouse brain, Mouse kidney

Target Information

This gene encodes a uridine 5′-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway.
The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase, which converts orotic acid to orotidine-5′-monophosphate.
The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase, which converts orotidine-5′-monophosphate to uridine monophosphate.
Defects in this gene cause hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

주의사항

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.