Thermo Fisher Scientific MYOD Polyclonal Antibody
MyoD 단백질을 검출하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합합니다. 인간, 마우스, 랫드, 영장류 시료에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MYOD1 (Accession P15172), corresponding to amino acid residues A90–P140 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900245 |
Product Specific Information
Antibody detects endogenous levels of total MyoD1.
Target Information
The Myogenic determination gene (MyoD) was first identified by its ability to convert embryonic mouse fibroblast cells into muscle cells. Forced expression of MyoD (human homolog: myf3) can induce muscle differentiation or activate muscle-specific genes in various cell types.
The regulatory domain of the MyoD gene product lies within a 70 amino acid region containing a basic DNA-binding motif and a helix-loop-helix (HLH) dimerization motif.
Other related genes sharing sequence homology in the basic HLH domain include myf5, myogenin (myf4), and myf6 (also known as MRF4 or herculin).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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