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Thermo Fisher Scientific Gpx3 Polyclonal Antibody
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Thermo Fisher Scientific Gpx3 Polyclonal Antibody

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Human과 Mouse에 반응하는 GPX3 단백질에 대한 Goat Polyclonal 항체로, Western blot 및 IHC에 사용 가능. 합성 펩타이드 면역원 기반으로 제작되었으며, 0.5 mg/mL 농도의 액상 형태로 제공. -20°C 보관, 연구용으로만 사용.

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pk
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마지막 업데이트 2025. 08. 04. 오후 03:25
Thermo Fisher Scientific PA518677 Gpx3 Polyclonal Antibody 100 ug pk판매 단위 pk ·
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650,100원VAT 포함 715,110원

Thermo Fisher Scientific · Thermo Fisher Scientific Gpx3 Polyclonal Antibody

Applications and Tested Dilution

Application Tested Dilution Publications
Western Blot (WB) 1–3 µg/mL -
Immunohistochemistry (IHC) - 1 publication
Immunohistochemistry (Paraffin) (IHC (P)) 3–5 µg/mL -
Immunohistochemistry (PFA fixed) (IHC (PFA)) 3–5 µg/mL -

Product Specifications

항목 내용
Species Reactivity Human, Mouse
Published Species Mouse
Host / Isotype Goat / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic peptide sequence (NQFGKQEPGENSE) corresponding to internal amino acids of GPX3 (aa 102–114)
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Purification Ammonium sulfate precipitation
Storage Buffer TBS, pH 7.3, with 0.5% BSA
Contains 0.02% sodium azide
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Wet ice
RRID AB_10980999

Product Specific Information

  • Predicted to react with canine, human, and rat based on sequence homology.
  • Tested in Peptide ELISA: antibody detection limit dilution 8,000.

Target Information

Glutathione peroxidases (Gpxs) are ubiquitously expressed enzymes that catalyze the reduction of hydrogen and organic hydroperoxides using glutathione.
There are several isoforms differing in structure and localization:

  • GPx1 (cGPx): Cytosolic/mitochondrial, selenium-dependent.
  • GPx2 (GI-GPx): Expressed in gastrointestinal epithelium.
  • GPx3 (pGPx): Extracellular plasma form, mainly produced by kidney and released into circulation.
  • GPx4 (PH-GPx): Reduces a variety of hydroperoxides including those in membranes and lipoproteins.

All mammalian GPx family members, except Cys-containing GPx3 and GPx5, contain selenocysteine at the active site.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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