Thermo Fisher Scientific MECOM Monoclonal Antibody (6A9)
Human MECOM 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot과 ELISA에 사용 가능. Affinity chromatography로 정제된 액상 형태이며, PBS(pH 7.4) buffer에 보존제 없이 제공. -20°C에서 보관, 연구용 전용 시약.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.03 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6A9 |
| Immunogen | MECOM (NP_005232, 952–1050 a.a.) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
YKSGLSALDH IRHFTDSLKM RKMEDNQYSE AELSSFSTSH VPEELKQPLH RKSKSQAYAM MLSLSDKESL HSTSHSSSNV WHSMARAAAE SSAIQSISH
Target Information
EVI1 (MECOM) is a transcriptional regulator and oncoprotein involved in hematopoiesis, apoptosis, development, cell differentiation, and proliferation.
It can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9.
The EVI1 gene may undergo translocation with the AML1 gene, leading to overexpression and leukemia onset.
Several transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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