Thermo Fisher Scientific EVI2B Monoclonal Antibody (2G9)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

0.1 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

2G9

Immunogen

EVI2B (NP_006486, 23 a.a. approximately 121 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EVI2B,uniProtId:P34910-1,ncbiNodeId:9606,antigenRange:23-121,antigenLength:448,antigenImageFileName:H00002124-M02_EVI2B_P34910-1_House_mouse.svg,antigenImageFileNamePDP:H00002124-M02_EVI2B_P34910-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: TETITTEKQS QPTLFTSSMS QVLANSQNTT GNPLGQPTQF SDTFSGQSIS PAKVTAGQPT PAVYTSSEKP EAHTSAGQPL AYNTKQPTPI ANTSSQQAV

Target Information

CD361, also known as EVI2B (Ecotropic Viral Integration site 2B) or EVDB, is a poorly characterized type I transmembrane protein, expressed from one of three genes embedded in intron 27b of the neurofibromatosis type 1 (NF1) gene. The DNA strand that is transcribed to produce CD361 is the complementary one to the strand encoding NF1. Murine homolog to human CD361 is associated with ecotropic viral insertions, which have been implicated in the expression of murine myeloid leukemias. CD361 has been also reported to be involved in melanocyte and keratinocyte differentiation. However, it is expressed mainly in peripheral blood and bone marrow.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.