Thermo Fisher Scientific PCDHGC5 Monoclonal Antibody (OTI1A6), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

• For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
• For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The PCDHGC5 gene belongs to the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome 5. These clusters exhibit immunoglobulin-like organization, suggesting a unique regulatory mechanism.
The gamma cluster includes 22 genes divided into subfamilies A (12 genes), B (7 genes + 2 pseudogenes), and C (3 genes). Each variable exon encodes the extracellular region with six cadherin ectodomains and a transmembrane region, while constant region exons encode a shared cytoplasmic domain.
These neural cadherin-like proteins likely contribute to specific cell-cell interactions in the brain. Alternative splicing has been reported for gamma cluster genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 없음)