Thermo Fisher Scientific PCDHGC5 Monoclonal Antibody (OTI1A6), TrueMAB
인간 PCDHGC5 단백질(아미노산 35-258)을 표적으로 하는 Mouse IgG1 단일클론 항체. Western blot에 적합하며, 동결건조 형태로 제공. PBS 버퍼(8% 트레할로스) 포함, 보존제 없음. -20°C 보관, 재구성 및 결합 실험에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 35–258 of human PCDHGC5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
- For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The PCDHGC5 gene belongs to the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome 5. These clusters exhibit immunoglobulin-like organization, suggesting a unique regulatory mechanism.
The gamma cluster includes 22 genes divided into subfamilies A (12 genes), B (7 genes + 2 pseudogenes), and C (3 genes). Each variable exon encodes the extracellular region with six cadherin ectodomains and a transmembrane region, while constant region exons encode a shared cytoplasmic domain.
These neural cadherin-like proteins likely contribute to specific cell-cell interactions in the brain. Alternative splicing has been reported for gamma cluster genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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