Thermo Fisher Scientific ADAM15 Polyclonal Antibody
ADAM15 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며, 인간 및 마우스 반응성. 고순도 Affinity Chromatography 정제, PBS/sucrose buffer에 보관. 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human ADAM15 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607931 |
Product Specific Information
- Peptide sequence: QPAAPLCLQT ANTRGNAFGS CGRNPSGSYV SCTPRDAICG QLQCQTGRTQ
- Sequence homology:
Cow: 86%
Dog: 79%
Guinea Pig: 79%
Horse: 85%
Human: 100%
Mouse: 100%
Pig: 85%
Rabbit: 79%
Rat: 100%
Target Information
The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) family. ADAM family members are type I transmembrane glycoproteins involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules.
This protein contains multiple functional domains including:
- Zinc-binding metalloprotease domain
- Disintegrin-like domain
- EGF-like domain
Through its disintegrin-like domain, the protein interacts with the integrin beta chain (β3) and Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting roles in cell-cell adhesion and signaling.
Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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