Thermo Fisher Scientific RMI1 Polyclonal Antibody

Applications

• Western Blot (WB): 0.2–1 µg/mL

Product Specifications

Product Specific Information

Peptide sequence:
DGILEIPKGE LNGFYALQIN SLVDVSQPAY SQIQKLRGKN TTNDLVTAEA

Sequence homology:
Cow: 93%
Dog: 100%
Guinea Pig: 93%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 93%
Rat: 93%

Target Information

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein. Through this mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
The protein kinase family includes more than 500 gene products and is classified into eight major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) includes kinases related to the MAPK cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, composed of a MAPK and upstream regulatory kinases (MAPKKs), are well characterized in the yeast pheromone response pathway.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.