Thermo Fisher Scientific Human RASSF10 Synthetic Peptide
인간 RASSF10 단백질의 N-말단 17개 아미노산 서열을 기반으로 한 합성 펩타이드. PA5-21151 항체의 블로킹 펩타이드로 사용 가능. 종 특이성은 인간이며, 액상 형태로 제공. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the amino terminus of human RASSF10.
PEP-1265 can be used as a blocking peptide with polyclonal antibody PA5-21151.
Target Information
RASSF10 is a member of the N-terminal Ras association domain-containing family of proteins, a family of tumor suppressor genes that are frequently epigenetically inactivated in cancer. These proteins consist of RASSF7–10 and are structurally distinct from RASSF1–6, containing the N-terminal Ras association domain but lacking the Sav/RASSF/Hippo protein interaction domains.
While little is known of the function of RASSF10, it is inactivated in both childhood leukemia and gliomas. In secondary glioblastomas, RASSF10 methylation can be used as an independent prognostic marker associated with worse progression-free survival and overall survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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