Thermo Fisher Scientific Human KAL1 Synthetic Peptide
인간 KAL1(Anosmin-1) 유래 합성 펩타이드로, PA5-21149 항체의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태이며 PBS(pH 7.2, 0.1% BSA) 용액에 보관. 연구용으로만 사용 가능. Kallmann 증후군 관련 연구에 적합.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the center of human Anosmin.
PEP-1263 can be used as a blocking peptide with polyclonal antibody PA5-21149.
Target Information
KAL1 (Anosmin-1) is an extracellular matrix-associated glycosylated protein linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell due to abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron.
Anosmin-1 directly binds FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of the FGF2-FGFR1-heparin complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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