Thermo Fisher Scientific Human TYW1 Synthetic Peptide
인간 TYW1 단백질의 C-말단 19개 아미노산 서열을 기반으로 한 합성 펩타이드. 항체 PA5-21152의 블로킹 펩타이드로 사용 가능. 고순도 정제 상태로 제공되며 PBS 완충액에 0.1% BSA 포함. 연구용으로만 사용.
- 카테고리
- Protein
- 판매단위
- pk
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Thermo Fisher Scientific Human TYW1 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the carboxy terminus of human TYW1.
PEP-1266 can be used as a blocking peptide with polyclonal antibody PA5-21152.
Target Information
TYW1 (also known as TYW1A, RSAFD1, YPL207W) is a 732 amino acid protein containing one flavodoxin-like domain that participates in the wybutosine-tRNA (Phe) biosynthesis pathway.
Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome.
TYW1 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during ribosomal decoding, ensuring correct translation.
TYW1 binds to one 4Fe-4S cluster and is located on human chromosome 7.
Defects in some genes on chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Lissencephaly, Citrullinemia, and Shwachman-Diamond syndrome, suggesting TYW1 may play a role in these conditions.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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