Thermo Fisher Scientific Thimet Oligopeptidase Polyclonal Antibody
Thimet Oligopeptidase(THOP1)를 인식하는 Sheep Polyclonal Antibody로, WB·IHC·IP에 사용 가능. 인간 반응성, 항원 친화 크로마토그래피 정제. 아밀로이드 베타 분해 연구 및 항원 제시 관련 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | 5–15 µg/mL | - |
| Immunoprecipitation (IP) | 25 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human Oligopeptidase/THOP1 (Lys2–Cys689) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608563 |
Product Specific Information
- In Western blots, less than 5% cross-reactivity with recombinant human Neurolysin is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of beta and gamma-secretases and its catabolism by proteolytic enzymes.
Thimet Oligopeptidase (THOP1) promotes A-beta degradation and plays roles in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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