Thermo Fisher Scientific SPR Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 200-261 of human SPR (P35270). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SPR,uniProtId:P35270-1,ncbiNodeId:9606,antigenRange:200-261,antigenLength:261,antigenImageFileName:PA5-121157_SPR_P35270-1_Rabbit.svg,antigenImageFileNamePDP:PA5-121157_SPR_P35270-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.66 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914729

Product Specific Information

Positive test controls include: HepG2, HeLa, COS-7, Jurkat, MCF7, Mouse liver, Mouse kidney, Mouse pancreas, Rat kidney. The target is usually found in the following locations: Cytoplasm.

Immunogen sequence: PLDTDMQQLA RETSVDPDMR KGLQELKAKG KLVDCKVSAQ KLLSLLEKDE FKSGAHVDFY DK

Target Information

SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.