Thermo Fisher Scientific ADAM12 Polyclonal Antibody
Thermo Fisher Scientific의 ADAM12 Polyclonal Antibody는 인간, 생쥐, 랫트에 반응하며 WB, IHC, ICC, ELISA에 사용 가능합니다. Rabbit IgG 기반의 비결합 액상 항체로, ADAM12 단백질 검출에 적합합니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific ADAM12 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 589–738 of human ADAM12 (NP_067673.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.26 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914730 |
Product Specific Information
Positive test controls include:
- Mouse brain
- Mouse thymus
- Mouse fat
- Mouse ovary
- Rat brain
The target is usually found in the following locations:
- Cell membrane
- Secreted
- Single-pass type I membrane protein
Immunogen sequence:
ASRPVIGTNA VSIETNIPLQ QGGRILCRGT HVYLGDDMPD PGLVLAGTKC ADGKICLNRQ CQNISVFGVH ECAMQCHGRG VCNNRKNCHC EAHWAPPFCD KFGFGGSTDS GPIRQAEARQ EAAESNRERG QGQEPVGSQE HASTASLTLI
Target Information
ADAM12 is a member of the ADAM (a disintegrin and metalloprotease-like domain) family. Two forms of ADAM12 have been described: ADAM12S and ADAM12L (short and long forms).
The short form is soluble, lacking transmembrane and cytoplasmic domains, and has been reported to provoke myogenesis. The lack of cytoplasmic domain suggests different regulation pathways, although both forms can be expressed in the same tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-121158_ADAM12_O43184-1_Rabbit.svg, PA5-121158_ADAM12_O43184-1_Rabbit_PDP.jpeg)
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