Thermo Fisher Scientific ADAM12 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 589-738 of human ADAM12 (NP_067673.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ADAM12,uniProtId:O43184-1,ncbiNodeId:9606,antigenRange:589-738,antigenLength:909,antigenImageFileName:PA5-121158_ADAM12_O43184-1_Rabbit.svg,antigenImageFileNamePDP:PA5-121158_ADAM12_O43184-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.26 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914730

Product Specific Information

Positive test controls include: Mouse brain, Mouse thymus, Mouse fat, Mouse ovary, Rat brain. The target is usually found in the following locations: Cell membrane, Secreted, Single-pass type I membrane protein.

Immunogen sequence: ASRPVIGTNA VSIETNIPLQ QGGRILCRGT HVYLGDDMPD PGLVLAGTKC ADGKICLNRQ CQNISVFGVH ECAMQCHGRG VCNNRKNCHC EAHWAPPFCD KFGFGGSTDS GPIRQAEARQ EAAESNRERG QGQEPVGSQE HASTASLTLI

Target Information

ADAM12 is a member of the ADAM (a disintegrin and metalloprotease-like domain) family. Two forms of ADAM12 have been described: ADAM12S and ADAM12L (short and long forms). The short form is a soluble form lacking the transmembrane and cytoplasmic domains. The short form of ADAM12 was reported to provoke myogenesis, and the lack of cytoplasmic domain suggests different regulation pathways (although both forms can be expressed in the same tissue).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.