Thermo Fisher Scientific Phospho-BLM (Ser1290) Polyclonal Antibody
인간 BLM 단백질의 Ser1290 인산화 형태를 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ELISA, IP에 사용 가능. 고순도 친화 크로마토그래피 정제. -20°C 보관, 반복 동결/해동 피함. 연구용 전용 시약.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Anti-BLM pS1290 affinity purified antibody prepared from whole rabbit serum immunized with a synthetic peptide corresponding to the internal region of human Bloom syndrome protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02 M potassium phosphate, pH 7.2, with 0.15 M NaCl, 10 mg/mL BSA |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
Anti-BLM pS1290 is directed against the phosphorylated form of human S1290 residue. A BLAST analysis suggests cross-reactivity with human and mouse based on 100% sequence homology. Cross-reactivity with BLM pS1290 from other sources has not been determined.
Target Information
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins, some of which are implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 acts as a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity, potentially involved in cellular signal transduction, inflammation, growth, and differentiation.
Annexin 5 is also known as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4, and anchorin CII. The gene spans 29 kb containing 13 exons and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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