Thermo Fisher Scientific MNK1 Recombinant Superclonal Antibody (6HCLC)
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
711542 | - | Thermo Fisher Scientific 711542 MNK1 Recombinant Superclonal Antibody (6HCLC) 100 ug pk | 재고문의 | pk | 653,000원 | - | 718,300원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1-2 µg/mL
Immunocytochemistry (ICC/IF)
2 µg/mL
Flow Cytometry (Flow)
-
View 1 publication 1 publication
Product Specifications
Species Reactivity
Human, Mouse
Published species
Mouse
Host/Isotype
Rabbit / IgG
Expression System
Expi293
Class
Recombinant Superclonal
Type
Antibody
Clone
6HCLC
Immunogen
Peptides corresponding to human MNK1 (aa38-57, aa9-26) if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
MNK1,
uniProtId:
Q9BUB5-1,
ncbiNodeId:
9606,
antigenRange:
9-26|38-57,
antigenLength:
465,
antigenImageFileName:
711542_MNK1_Q9BUB5-1_Rabbit.svg,
antigenImageFileNamePDP:
711542_MNK1_Q9BUB5-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2662014
Product Specific Information
This antibody is predicted to react with Monkey, Mouse, Cat
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and the performance remain unchanged.
Target Information
The Map kinase-interacting kinases (MKNK1 and MKNK2) are activated by Map kinases, regulate protein synthesis by phosphroylation eIF4E on Ser209, and may contribute to tumorigenesis. Overexpression of Mnk2 results in increased phosphorylation of endogenous eIF-4E, showing that it can act as an eIF-4E kinase in vivo. Mnk2 may play a role in the response to environmental stress and cytokines. Expression of active mutants of MNK1 and MNK2 in 293 cells diminishes cap-dependent translation relative to cap-independent translation in a transient reporter assay. Human Mnk2 is homologous to murine Mnk2 (approximately 94% identical) and human Mnk1 (71% identical). In vitro phosphorylation studies show that Mnk2 is a significantly better substrate than Mnk1 for extracellular signal-regulated kinase 2 (Erk2), p38MAPKalpha, and p38MAPKbeta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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