Thermo Fisher Scientific Thromboxane synthase Polyclonal Antibody
인체 Thromboxane synthase를 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:500~1:1,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 완충액에 보관. 혈소판 응집 및 혈관 수축 관련 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TBXAS1. Recombinant protein control fragment: Product #RP-95560 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648299 |
Product Specific Information
Immunogen sequence:
RGALMSAFSP EKLNEMVPLI SQACDLLLAH LKRYAESGDA FDIQRCYCNY TTDVVASVAF GTPVDSWQAP EDPFVKHCKR FFEFCIP
Ortholog sequence identity:
- Mouse: 78%
- Rat: 77%
Target Information
Thromboxane synthase encodes a member of the cytochrome P450 superfamily of enzymes. These proteins are monooxygenases that catalyze reactions involved in drug metabolism and the synthesis of cholesterol, steroids, and other lipids. Although classified as a P450 enzyme by sequence similarity, its function is distinct. This endoplasmic reticulum membrane protein catalyzes the conversion of prostaglandin H2 to thromboxane A2, a potent vasoconstrictor and platelet aggregation inducer. It plays roles in hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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