Thermo Fisher Scientific Thromboxane synthase Polyclonal Antibody
인간 Thromboxane synthase를 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:500~1:1,000 희석 비율로 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol, 0.02% sodium azide)에 보관. 단백질 발현 연구 및 혈전 관련 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TBXAS1. Recombinant protein control fragment (Product # RP-95558) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2648300 |
Product Specific Information
Immunogen sequence:
PDCQEKLLRE VDVFKEKHMA PEFCSLEEGL PYLDMVIAET LRMYPPAFRF TREAAQDCEV LGQRIPAGAV LEMAVGALHH DPEH
- Highest antigen sequence identity to orthologs:
- Mouse: 86%
- Rat: 85%
Target Information
Thromboxane synthase encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
This endoplasmic reticulum membrane protein catalyzes the conversion of prostaglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation.
The enzyme is involved in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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