Thermo Fisher Scientific BCLAF1 Polyclonal Antibody
BCLAF1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 면역세포화학에 적합합니다. 인간에 반응하며, 예측 반응성으로 마우스·랫·돼지·소에서도 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human BTF |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792795 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (94%), Rat (94%), Pig (98%), Bovine (98%).
- Positive Control: 293T, A431, HeLa, HepG2.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
BCLAF1 is an intracellular, death-promoting transcriptional repressor of survival genes that interacts with several members of the BCL2 family of proteins.
It shows homology to the basic leucine zipper (bZIP) and MYB DNA binding domains.
In apoptotic cells, this protein localizes to dot-like structures throughout the nucleus and redistributes near the nuclear envelope.
When overexpressed, BCLAF1 induces apoptosis, which can be suppressed by co-expression of BCL2 proteins.
Also known as BTF, it triggers a proapoptotic signal and is mainly expressed in skeletal muscles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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