Thermo Fisher Scientific KISS1 Polyclonal Antibody
Thermo Fisher Scientific의 KISS1 Polyclonal Antibody는 인간 및 랫트 시료에 반응하는 토끼 유래 다클론 항체입니다. Western blot에 적합하며, KISS1 단백질 연구에 사용됩니다. 항원 친화 정제 방식으로 제조되었으며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
- 카탈로그번호
- PA585657
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center of human Kiss1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2792796 |
Product Specific Information
- Keep as concentrated solution.
- Positive Control: Jurkat, Raji, NCI-H929, mouse testis, rat testis.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The KISS1 gene functions as a metastasis suppressor, inhibiting metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may reduce chemotaxis and invasion, thereby attenuating metastasis in malignant melanomas.
Studies indicate its role in regulating cell-matrix adhesion events, possibly involving cytoskeletal reorganization. The protein product, kisspeptin, stimulates GnRH-induced gonadotropin secretion and regulates pubertal activation of GnRH neurons.
A polymorphism in the terminal exon of this mRNA produces two isoforms; when an adenosine is absent at the polymorphic site, a downstream stop codon is used, resulting in a protein extended by seven amino acids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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