Thermo Fisher Scientific Etv5 Polyclonal Antibody
Etv5 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. Human 및 Mouse 반응성, Rabbit IgG 포맷. 고순도 Protein A 정제, 안정적 액상 형태로 연구용 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ERM/Etv5, amino acids 301–385 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ETS variant 5 (ETV5) is a transcription factor of the ETS family and a divergent member of the winged helix-turn-helix superfamily. It is expressed in brain, placenta, and other tissues involved in development.
Tissue specificity: Ubiquitous. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that ETV5 is required for SSC self-renewal but not differentiation, resulting in progressive germ cell depletion in affected mice.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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