Thermo Fisher Scientific Plexin-A3 (extracellular) Polyclonal Antibody
Plexin-A3 단백질의 세포외 영역을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체입니다. Western blot, IHC, Flow cytometry 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. Lyophilized 형태로 제공되며 안정적인 저장이 가능합니다.
- 카탈로그번호
- APR-093-xxxxx (3개 옵션)
- 판매단위
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3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Plexin-A3 (extracellular) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:200 |
| Flow Cytometry (Flow) | 2.5 µg |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)KVRVDGSQDAQLYE, corresponding to amino acid residues 440–453 of mouse PLXNA3, extracellular N-terminus |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size
- Ships as a lyophilized powder at room temperature
- Store at -20°C upon arrival
- Reconstituted solution can be stored at 4°C for up to 1 week
- For long-term storage, aliquots should be kept at -20°C
- Avoid multiple freeze/thaw cycles
- Centrifuge all antibody preparations before use (10,000 × g, 5 min)
Target Information
Plexin-A3 acts as a coreceptor for SEMA3A and SEMA3F, essential for signaling by class 3 semaphorins and cytoskeletal remodeling. It plays a key role in axon guidance within the developing nervous system and regulates migration of sympathetic neurons. Plexin-A3 is required for normal dendritic spine morphology in pyramidal neurons and may influence semaphorin-mediated programmed cell death. Class 3 semaphorins bind to a complex of neuropilin and plexin, where plexin modulates affinity and activates downstream signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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