Thermo Fisher Scientific DCLK1 Monoclonal Antibody (OTI1F8), TrueMAB

Applications

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

DCAMKL1 (DCLK1), also known as doublecortin-like kinase 1, is a serine/threonine kinase containing two N-terminal doublecortin domains that bind microtubules and regulate microtubule polymerization. It also possesses a C-terminal serine/threonine protein kinase domain homologous to Ca²⁺/calmodulin-dependent protein kinase and a serine/proline-rich domain that mediates protein-protein interactions.
DCLK1 is a microtubule-associated kinase capable of autophosphorylation and has microtubule-polymerizing activity independent of its kinase function. It is involved in neuronal migration, retrograde transport, apoptosis, and neurogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.