Thermo Fisher Scientific NRF1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.2–1 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:600

Product Specifications

Product Specific Information

• Peptide sequence:
  WATLQGGEMT IQTTQASEAT QAVASLAEAA VAASQEMQQG ATVTMALNSE

• Sequence homology:
  Cow: 100%
  Dog: 100%
  Guinea Pig: 100%
  Horse: 100%
  Human: 100%
  Mouse: 100%
  Rabbit: 100%
  Rat: 100%
  Zebrafish: 100%

Target Information

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants encoding the same protein have been characterized. Additional variants encoding different protein isoforms have been described but not fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for nuclear factor (erythroid-derived 2)-like 1 (official symbol NFE2L1).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.