Thermo Fisher Scientific MIER1 Polyclonal Antibody
Thermo Fisher Scientific의 MIER1 Polyclonal Antibody는 인간 MIER1 단백질을 인식하는 토끼 IgG 항체입니다. Western blot에 최적화되어 있으며, Protein A로 정제된 고순도 항체입니다. 합성 펩타이드를 면역원으로 사용하며, -20°C에서 보관 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1.25 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human MIER1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606741 |
Product Specific Information
- Peptide sequence: RRTGDEKGVE AIPEGSHIKD NEQALYELVK CNFDTEEALR RLRF
- Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Target Information
The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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