Thermo Fisher Scientific CBX7 Polyclonal Antibody
CBX7 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, ICC/IF, ChIP assay에 적합합니다. 인간 시료에 반응하며, 고순도의 Affinity Chromatography로 정제되었습니다. PBS 완충액에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ChIP assay (ChIP) | 2.5 µg/10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human CBX7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609869 |
Product Specific Information
Peptide sequence:
ADLAEGPPPW TPALPSSEVT VTDITANSIT VTFREAQAAE GFFRDRSGKF
Sequence homology:
Cow: 100%
Dog: 93%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 93%
Rabbit: 100%
Rat: 100%
Target Information
The protein encoded by this gene is one subunit of a trimeric complex forming a highly conserved transcription factor that binds to CCAAT motifs in promoter regions of various genes.
Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity.
The sequence-specific interactions of the complex are made by the A subunit, suggesting a regulatory role.
Post-transcriptional regulation may occur via protein degradation or translational control.
Alternative splicing in the glutamine-rich activation domain provides tissue-specific isoform expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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